Lowering homocysteine with TMG

• TMG 1 g, mornings · 2025-06-16 → 2025-07-10. Homocysteine went 10.76 → 7.42 within six weeks of starting.
• Off TMG through the autumn → drifted back up to 8.09.
• TMG 2 g, mornings · restarted 2025-11-11, ongoing. Next draw: 7.29.

Co-interventions I can't fully separate: methyl B-12 (1 mg daily) started four days after the first TMG run; methylfolate (every other day) added 2026-01.

The 11.48 on 2026-03-12 stood out — the highest reading in the series, and I was still on 2 g TMG daily. It isn't a mystery anymore.

The two to three months before that draw were the worst-controlled stretch of the year: travelling, eating out most days, a worse diet overall, and short sleep in the couple of weeks right before the blood test. Homocysteine tracks exactly that — B-vitamin intake and the folate/B12 status behind it — so a spike there is what you'd expect, TMG or not.

Once the normal routine came back, so did the number: 9.89 a month later, then 8.82 on 2026-06-11, back near the on-TMG baseline (and that June draw also followed a short-sleep week — the low end of "normal for me").

So the honest read isn't "TMG fixed it and it stays fixed." It's "TMG lowers it, and diet + sleep can push it right back up." Both levers matter, and the March draw is the proof of the second one — I'm keeping it in the record for exactly that reason.