What moved my ApoB? An honest cross-reference
ApoB went 118 → 75 → back to 95 → 82. I lined every swing up against my dose-period history. One correlate survives; no proof.
The swings
| date | ApoB | LDL (calc) | Total chol | HDL |
|---|---|---|---|---|
| 2023-12-07 | 94.2 | 125.4 | 197 | 61 |
| 2024-10-31 | 118.2 | 130.6 | 204 | 63 |
| 2025-06-05 | 96.9 | 136.2 | 220 | 72 |
| 2025-07-29 | — | 115.8 | 190 | 65 |
| 2025-10-29 | 75.4 | 105.2 | 180 | 64 |
| 2025-12-16 | 95.1 | 132.8 | 210 | 65 |
| 2026-03-12 | 81.9 | 111.0 | 191 | 68 |
Triglycerides stayed 46–65 throughout — never part of the story. | 2026-06-11 | 84.7 | 120 | 205 | 72 |
Lining the swings up against the stack
Context that holds still: diet has been the same for years — high-protein Mediterranean, extra-virgin olive oil as the main fat. So food is off the suspect list for every swing below. Training was steady too (full-body gym 2–4×/week + sports for cardio), with two exceptions that matter.
The 118 peak (Oct 2024): that draw sits in my back-problem year — for a good chunk of 2024 I trained much less, sometimes not at all. A deconditioned stretch is a credible explanation for the worst ApoB reading in the series.
The big drop (Jun → Oct 2025, ApoB 97 → 75): training and diet normal and stable. Started in that window — TMG (Jun–Jul), methyl B-12 daily (Jun 20 → Oct 1), akkermansia (Jul 21 → Oct 19), selenium EOD + boron 6 mg (Aug 9), L-tyrosine (Sep 9). The mid-window draw (Jul 29) shows most of the LDL drop had already happened by late July.
The rebound (Oct → Dec 2025, ApoB 75 → 95): stopped akkermansia (Oct 19), dropped B-12 from daily to ~weekly (Oct 1). TMG restarted at 2 g (Nov 11) and didn't prevent it. Training unchanged.
The re-improvement (Dec → Mar 2026, ApoB 95 → 82): B-12 back to daily (Jan 20), selenium daily (Jan 20), methylfolate added (Jan 22) — and from February, tennis elbow ended sports but pushed gym volume UP to 4–5 full-body sessions a week. Two things changed at once; this leg can't separate them.
What survives, and what I can't claim
With diet stable for years, the cleanest evidence is the 2025 mid-year drop and the autumn rebound — both under unchanged training: methyl B-12 taken daily is present in every low-ApoB phase and sparse or absent in the rebound. Akkermansia fits 2025 but I re-improved in 2026 without it. The 2024 peak now has a rival explanation (the low-training back year), and the 2026 re-improvement is confounded by the training increase after tennis elbow took sports away.
What this is not: proof. Nothing was controlled, the readings are quarterly at best, and homocysteine doesn't co-move the way a clean methylation story would predict (it spiked in Mar 2026 while ApoB improved). Correlation from one person's log, nothing more.
Update, 2026-06-11: ApoB drifted to 84.7 (LDL 120). Nothing changed in the stack; the draw followed a short-sleep week and I'd let training slip a little around it. Consistent with the rest of this log — the swings are real but small, and no single input owns them.